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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TARDBP
All Species:
13.33
Human Site:
S347
Identified Species:
36.67
UniProt:
Q13148
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13148
NP_031401.1
414
44740
S347
L
A
S
Q
Q
N
Q
S
G
P
S
G
N
N
Q
Chimpanzee
Pan troglodytes
XP_001135126
357
37996
N295
N
Q
S
G
P
S
G
N
N
Q
N
Q
G
N
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921F2
414
44529
S347
L
A
S
Q
Q
N
Q
S
G
P
S
G
N
N
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515386
295
33249
T233
F
R
A
F
A
F
V
T
F
A
D
D
Q
V
A
Chicken
Gallus gallus
Q5ZLN5
414
44571
S347
L
A
S
Q
Q
N
Q
S
G
P
S
G
N
N
Q
Frog
Xenopus laevis
Q6NU14
291
32937
D229
Q
G
Y
S
N
Y
Y
D
Q
N
Y
G
G
Y
G
Zebra Danio
Brachydanio rerio
NP_958884
412
44409
S349
Q
Q
N
Q
S
G
T
S
G
T
S
T
S
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392590
466
50438
Q388
L
Q
N
Q
G
N
D
Q
G
Y
S
N
Q
P
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
T451
N
K
S
N
D
V
Q
T
I
G
N
T
S
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
N.A.
N.A.
N.A.
96.1
N.A.
N.A.
66.6
95.1
22.7
76
N.A.
N.A.
49.5
N.A.
N.A.
Protein Similarity:
100
86.2
N.A.
N.A.
N.A.
98.7
N.A.
N.A.
69.5
97.3
38.4
86.4
N.A.
N.A.
63
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
100
N.A.
N.A.
0
100
6.6
26.6
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
100
33.3
N.A.
N.A.
N.A.
100
N.A.
N.A.
13.3
100
6.6
40
N.A.
N.A.
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
12
0
12
0
0
0
0
12
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
12
12
0
0
12
12
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
12
0
0
12
0
12
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
12
0
12
12
12
12
0
56
12
0
45
23
12
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
23
0
23
12
12
45
0
12
12
12
23
12
34
56
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
34
0
0
0
12
0
% P
% Gln:
23
34
0
56
34
0
45
12
12
12
0
12
23
0
34
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
56
12
12
12
0
45
0
0
56
0
23
0
0
% S
% Thr:
0
0
0
0
0
0
12
23
0
12
0
23
0
0
23
% T
% Val:
0
0
0
0
0
12
12
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
12
12
0
0
12
12
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _